Application of Spectroscopy Techniques for Monitoring (Bio)Catalytic Processes in Continuously Operated Microreactor Systems

In the last twenty years, application of microreactors in chemical and biochemical industrial processes has increased significantly. The use microreactor systems ensures efficient process intensification due to excellent heat mass transfer within microchannels. Monitoring concentrations microchannels is critical for a better understanding physical occurring micromixers microreactors. Therefore, there growing interest performing in-line on-line analyses and/or processes. This creates tremendous opportunities incorporation spectroscopic detection techniques into production processing lines various industries. this work, an overview current applications ultraviolet–visible, infrared, Raman spectroscopy, NMR, MALDI-TOF-MS, ESI-MS monitoring (bio)catalytic continuously operated presented. manuscript includes description advantages disadvantages analytical methods listed, with particular emphasis on chemometric used data analysis.